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Filling and sealing linkage production line

The filling and sealing production linkage line is mainly applicable to the process of bottle management, bottle sending, quantitative filling, stoppering, and capping of various small doses and small batches of water/powder, such as oral liquid, syrup, essential oil, injection, etc. Widely used in the pharmaceutical, food, health care, electronics, chemical industry and scientific research fields.

Core Advantages
Core Technology
Technical Parameters
Application Scenarios
Optional Systems

1. Performance
- The design, materials, manufacturing, assembly and commissioning of the entire bottle filling line are in accordance with the new GMP and FDA regulations.
- Applications: 1ml - 50ml (according to user specifications);
- Capacity of bottle filling machine : 300-3000bhp
- Filling head of bottle filling machine: 1-4 pcs, choose according to capacity;
- Various types of filling pump options: glass pump, metal pump, peristaltic pump, ceramic pump;
- Filling accuracy: ≤±1% (according to the characteristics of the medicine);
- Sealing method: screw cap, rolled cap or screw threaded cap
- Pass rate: ≥99%
- The equipment is intuitive and easy to operate, simple in structure, stable in performance and accurate in loading;
- Bottles are loaded by a turntable or a mesh belt;
- Pneumatic pressurisation of the plugs with a high pass rate;
- The capping is carried out using robotic cap gripping technology or automatic cap dropping, which does not generate aluminium dust pollution;
- With fibre optic sensing, with no bottle no filling and no caping function;
- Servo motor-controlled filling pumps can be configured to carry out filling with high filling accuracy and easy adjustment;
- The nitrogen filling unit can be configured to isolate the medicinal solution from oxygen;
- Configurable with Open-RABS isolation protection system and Class 100 air purification laminar flow system;
- Fully automatic control and monitoring of the production process using control technologies such as high-precision colour touch screen operation and monitoring, PLC automatic control, automatic protection and mainframe variable frequency speed regulation;
- Can customized relevant products according to the actual needs of the customer.

Why MARYA

Trusted Worldwide

20 +

Years rich Industry Experience

3 +

Production Bases

60 +

Successful Projects in 60 Countries

300 +

Loyal Clientele

Company Honors and Certificates

CE Bottle unscrambler and labeling machine

Some of Our Customers

Well - known visiting Clients

Invited to the Embassy of the United Republic of Tanzania in Guangzhou to discuss projects

Tanzanian Vice President Visits Marya Pharmaceutical EPC Project

NBA (Zimbabwe National Biotechnology Authority) conducts FAT at MARYA’s Factory

NOVO NORDISK client Visit

Clients visit the factory's liquid preparation system

Argentine client visits for FAT in MARYA

Successful Cases

Zimbabwe Vial Filling Line

Malaysia Prefilled Syringe Filling line

Argentina Vial and Ampoule line

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Services

Full-process Consulting Services

Whether you are preparing to build a new pharmaceutical factory, build a cleanroom that complies with local GMP regulations, or purchase pharmaceutical equipment to develop a new production line, whether it is a separate cleanroom or pharmaceutical machine project, or a one-stop solution, Marya's professional teams in the fields of pharmaceutical technical process, process equipment, decoration engineering, HVAC engineering, pipeline engineering, utility equipment, intelligent automatic control systems, project cost and other fields can provide you with full-process technical consulting services, and solve your needs one-on-one.

2D/3D Design Modeling Services

Marya project design team is composed of professional CAD and BIM engineers with more than 20 years of comprehensive industry experience and can provide you with comprehensive design services, including but not limited to process layout drawings, technical process charts, 3D models and animations, air conditioning system scheme design, construction drawing design, plant/pharmaceutical machine layout drawings, etc.

Machine Customization Services

Based on the individual needs of clients in different countries, Marya helps you clarify specific needs, match appropriate models, and customize one stop filling solutions for sterile small-volume preparations, large-volume injections, oral liquids/syrups, solid preparations, etc.

Validation Services (FAT/SAT)

Marya will appoint an engineer with rich project management experience as the person in charge, who will be fully responsible for project management and liaison work. After the equipment is manufactured, our engineers and the buyer's representatives will participate in the FAT test. After the equipment arrives at the buyer's site, it will be installed and debugged. After the equipment reaches optimal operation, the buyer will conduct SAT testing and inspection.

Customer FAQ

Are you manufacturer or trader? Where are your factory located?

We are manufacturer. Our factory is located in Changsha and Suzhou.

What certificate do you have?

We have CE, ISO, ROHS, SGS etc.

What documents will you provide?

Usually we will provide DQ, IQ, PQ, OQ, FAT, SAT, operation manual, maintenance instruction,layout drawing.etc.

What is the production lead time?

Standard 25-60 days after deposit received and technical data confirmed, we can make special arrangement for better shipment if needed;
Standard 60-150 days after deposit received and technical data confirmed based on different machines, we can make special arrangement for better shipment if needed.

How long is your warranty? Can we extend?

12 months after installation and commissioning or 18 moths from the day that the equipment arrived on site. Prevail in the first arrival date.
Warranty can be extended with extra charge.

Have you done similar projects overseas?

Marya’s business map covers more than 60 countries and regions around the world, such as the United States, Russia, Bulgaria, Britain, Portugal, Poland, Switzerland, ltaly, New Zealand, Malta, Moldova, Malaysia, Uzbekistan, lran, Egypt, Saudi Arabia, UAE, Ecuador, Dominica, Panama, Uruguay, Argentina, Tanzania, Zimbabwe, Ethiopia, Indonesia, Bangladesh, and others, and we gained good reputation.

Key words:

Filling and sealing linkage production line

bottle filling machine

bottle filling line

Vacuum freeze dryer

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