Packaging Material Selection: Prefilled Syringes

2024-03-26

Marya has extensive experience in aseptic filling and has delivered more than 300 business. The important concerns for the prefilled syringe process are "aseptic manufacturing" and "filling efficiency". Marya’s aseptic filling line and prefilling system can achieve high accuracy and stable sterility assurance. The filling range of prefilled syringe and cartridge is 1mL to 20mL and the filling speed is 12,000 per hour.

Before the prefilled syringes are used, ampoules are initially applied. Before injection, the bottle neck of ampoules is broken, and then the liquid medicine is drawn by syringe and injected into the human body. The risk is that the sharp glass is easy to cut the skin, and the residual liquid medicine is easy to cause adverse reactions of people who contact it. In addition, an additional syringe is required besides ampoules. With years of development and the efforts of researchers, a new packaging form that liquid medicine is loaded in the syringe superior to ampoules, namely prefilled syringe, appears.

Firstly, prefilled syringe has the advantages of being easy to use, reducing contamination and accurate dosing. Compared to traditional dosage form of biological products, prefilled syringe is easier to use, reducing drug waste and use errors. It also reduces contamination and the risk of bacterial and viral infections during delivery and use of the drug. In addition, it has the characteristic of accurate dosage, which can avoid problems such as too high or too low dosage caused by improper use.

Secondly, prefilled syringe can be applied to a variety of biological products, including biosimilars, monoclonal antibodies and vaccines. As a new dosage form, it can not only expand the application scope of biological products, but also improve the efficacy and safety of biological products.

Thirdly, with the increasing demand for biological products and the continuous improvement of technology, the market prospect of prefilled syringe is broader especially in vaccine, monoclonal antibody, biosimilars and other areas. In the global market, it is expected to grow at an annual rate of 13.3%, and the market value is expected to reach $18 billion by 2026.

Finally, the prospect of prefilled syringe faces some challenges.
The production cost of prefilled syringe is relatively high, which requires a large amount of research and development funds and technical support.
The market competition for prefilled syringe is fierce and requires strong technical strength.
The application safety and reliability of prefilled syringe also need to be further strengthened.

Marya Prefilled Syringe Filling Line:

Applications: 1ml - 20ml (according to user specifications);
Filling range of plastic pfs machine: 0.1ml-20ml
Capacity: 2000-30000 bph
Filling head: 2-10 PCS, choose according to capacity;
Various types of filling pump options: metal pump, peristaltic pump, ceramic pump;
Filling accuracy: ≤ ± 1% (depending on the characteristics of the medicine).
Pass rate ≥99.9%
Automatic removal and return of the syringe from the honeycomb tray by means of a servo system combined with a cylinder;
Fully automatic production control with intelligent testing devices at the core stations;

Marya's Vial Filling Line-Flexibility and High-Performance

Introduction Cleanroom Plane Layout